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cGMP-Phosphodiesterase Inhibition Enhances Photic Responses and Synchronization of the Biological Circadian Clock in Rodents

The master circadian clock in mammals is located in the hypothalamic suprachiasmatic nuclei (SCN) and is synchronized by several environmental stimuli, mainly the light-dark (LD) cycle. Light pulses in the late subjective night induce phase advances in locomotor circadian rhythms and the expression...

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Detalles Bibliográficos
Autores principales: Plano, Santiago A., Agostino, Patricia V., de la Iglesia, Horacio O., Golombek, Diego A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349644/
https://www.ncbi.nlm.nih.gov/pubmed/22590651
http://dx.doi.org/10.1371/journal.pone.0037121