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Hydrogen Sulfide Inhibits L-Type Calcium Currents Depending upon the Protein Sulfhydryl State in Rat Cardiomyocytes

Hydrogen sulfide (H(2)S) is a novel gasotransmitter that inhibits L-type calcium currents (I (Ca, L)). However, the underlying molecular mechanisms are unclear. In particular, the targeting site in the L-type calcium channel where H(2)S functions remains unknown. The study was designed to investigat...

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Detalles Bibliográficos
Autores principales: Zhang, Rongyuan, Sun, Yan, Tsai, Haojan, Tang, Chaoshu, Jin, Hongfang, Du, Junbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349658/
https://www.ncbi.nlm.nih.gov/pubmed/22590646
http://dx.doi.org/10.1371/journal.pone.0037073