Cargando…
Distinct RGK GTPases Differentially Use α(1)- and Auxiliary β-Binding-Dependent Mechanisms to Inhibit Ca(V)1.2/Ca(V)2.2 Channels
Ca(V)1/Ca(V)2 channels, comprised of pore-forming α(1) and auxiliary (β,α(2)δ) subunits, control diverse biological responses in excitable cells. Molecules blocking Ca(V)1/Ca(V)2 channel currents (I (Ca)) profoundly regulate physiology and have many therapeutic applications. Rad/Rem/Rem2/Gem GTPases...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349659/ https://www.ncbi.nlm.nih.gov/pubmed/22590648 http://dx.doi.org/10.1371/journal.pone.0037079 |