Differential Neuregulin 1 Cleavage in the Prefrontal Cortex and Hippocampus in Schizophrenia and Bipolar Disorder: Preliminary Findings

BACKGROUND: Neuregulin 1 (NRG1) is a key candidate susceptibility gene for both schizophrenia (SCZ) and bipolar disorder (BPD). The function of the NRG1 transmembrane proteins is regulated by cleavage. Alteration of membrane bound-NRG1 cleavage has been previously shown to be associated with behavio...

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Detalles Bibliográficos
Autores principales: Marballi, Ketan, Cruz, Dianne, Thompson, Peter, Walss-Bass, Consuelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349664/
https://www.ncbi.nlm.nih.gov/pubmed/22590542
http://dx.doi.org/10.1371/journal.pone.0036431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349664/
https://www.ncbi.nlm.nih.gov/pubmed/22590542
http://dx.doi.org/10.1371/journal.pone.0036431

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