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Differential Neuregulin 1 Cleavage in the Prefrontal Cortex and Hippocampus in Schizophrenia and Bipolar Disorder: Preliminary Findings
BACKGROUND: Neuregulin 1 (NRG1) is a key candidate susceptibility gene for both schizophrenia (SCZ) and bipolar disorder (BPD). The function of the NRG1 transmembrane proteins is regulated by cleavage. Alteration of membrane bound-NRG1 cleavage has been previously shown to be associated with behavio...
Autores principales: | Marballi, Ketan, Cruz, Dianne, Thompson, Peter, Walss-Bass, Consuelo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349664/ https://www.ncbi.nlm.nih.gov/pubmed/22590542 http://dx.doi.org/10.1371/journal.pone.0036431 |
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