Insight into the Stability of Cross-β Amyloid Fibril from VEALYL Short Peptide with Molecular Dynamics Simulation

Amyloid fibrils are found in many fatal neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, type II diabetes, and prion disease. The VEALYL short peptide from insulin has been confirmed to aggregate amyloid-like fibrils. However, the aggregation mechanism of amyloi...

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Detalles Bibliográficos
Autores principales: Ye, Wei, Chen, Yue, Wang, Wei, Yu, Qingfen, Li, Yixue, Zhang, Jian, Chen, Hai-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349666/
https://www.ncbi.nlm.nih.gov/pubmed/22590535
http://dx.doi.org/10.1371/journal.pone.0036382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349666/
https://www.ncbi.nlm.nih.gov/pubmed/22590535
http://dx.doi.org/10.1371/journal.pone.0036382

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