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Insight into the Stability of Cross-β Amyloid Fibril from VEALYL Short Peptide with Molecular Dynamics Simulation
Amyloid fibrils are found in many fatal neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, type II diabetes, and prion disease. The VEALYL short peptide from insulin has been confirmed to aggregate amyloid-like fibrils. However, the aggregation mechanism of amyloi...
Autores principales: | Ye, Wei, Chen, Yue, Wang, Wei, Yu, Qingfen, Li, Yixue, Zhang, Jian, Chen, Hai-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349666/ https://www.ncbi.nlm.nih.gov/pubmed/22590535 http://dx.doi.org/10.1371/journal.pone.0036382 |
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