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Factors Determining Sensitivity and Resistance of Tumor Cells to Arsenic Trioxide

Previously, arsenic trioxide showed impressive regression rates of acute promyelocytic leukemia. Here, we investigated molecular determinants of sensitivity and resistance of cell lines of different tumor types towards arsenic trioxide. Arsenic trioxide was the most cytotoxic compound among 8 arseni...

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Detalles Bibliográficos
Autores principales: Sertel, Serkan, Tome, Margaret, Briehl, Margaret M., Bauer, Judith, Hock, Kai, Plinkert, Peter K., Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349672/
https://www.ncbi.nlm.nih.gov/pubmed/22590507
http://dx.doi.org/10.1371/journal.pone.0035584