Dissociation between Mature Phenotype and Impaired Transmigration in Dendritic Cells from Heparanase-Deficient Mice

To reach the lymphatics, migrating dendritic cells (DCs) need to interact with the extracellular matrix (ECM). Heparanase, a mammalian endo-β-D-glucuronidase, specifically degrades heparan sulfate proteoglycans ubiquitously associated with the cell surface and ECM. The role of heparanase in the phys...

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Detalles Bibliográficos
Autores principales: Benhamron, Sandrine, Reiner, Inna, Zcharia, Eyal, Atallah, Mizhir, Grau, Amir, Vlodavsky, Israel, Mevorach, Dror
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349677/
https://www.ncbi.nlm.nih.gov/pubmed/22590508
http://dx.doi.org/10.1371/journal.pone.0035602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349677/
https://www.ncbi.nlm.nih.gov/pubmed/22590508
http://dx.doi.org/10.1371/journal.pone.0035602

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