A Quantitative Study of the Mechanisms behind Thymic Atrophy in Gαi2-Deficient Mice during Colitis Development

Mice deficient for the G protein subunit Gαi2 spontaneously develop colitis, a chronic inflammatory disease associated with dysregulated T cell responses. We and others have previously demonstrated a thymic involution in these mice and an aberrant thymocyte dynamics. The Gαi2(−/−) mice have a dramat...

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Detalles Bibliográficos
Autores principales: Elgbratt, Kristina, Jansson, Andreas, Hultgren-Hörnquist, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349706/
https://www.ncbi.nlm.nih.gov/pubmed/22590596
http://dx.doi.org/10.1371/journal.pone.0036726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349706/
https://www.ncbi.nlm.nih.gov/pubmed/22590596
http://dx.doi.org/10.1371/journal.pone.0036726

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