Differential Pathogenesis of Lung Adenocarcinoma Subtypes Involving Sequence Mutations, Copy Number, Chromosomal Instability, and Methylation

BACKGROUND: Lung adenocarcinoma (LAD) has extreme genetic variation among patients, which is currently not well understood, limiting progress in therapy development and research. LAD intrinsic molecular subtypes are a validated stratification of naturally-occurring gene expression patterns and encom...

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Detalles Bibliográficos
Autores principales: Wilkerson, Matthew D., Yin, Xiaoying, Walter, Vonn, Zhao, Ni, Cabanski, Christopher R., Hayward, Michele C., Miller, C. Ryan, Socinski, Mark A., Parsons, Alden M., Thorne, Leigh B., Haithcock, Benjamin E., Veeramachaneni, Nirmal K., Funkhouser, William K., Randell, Scott H., Bernard, Philip S., Perou, Charles M., Hayes, D. Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349715/
https://www.ncbi.nlm.nih.gov/pubmed/22590557
http://dx.doi.org/10.1371/journal.pone.0036530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349715/
https://www.ncbi.nlm.nih.gov/pubmed/22590557
http://dx.doi.org/10.1371/journal.pone.0036530

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