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Filament Compliance Influences Cooperative Activation of Thin Filaments and the Dynamics of Force Production in Skeletal Muscle

Striated muscle contraction is a highly cooperative process initiated by Ca(2+) binding to the troponin complex, which leads to tropomyosin movement and myosin cross-bridge (XB) formation along thin filaments. Experimental and computational studies suggest skeletal muscle fiber activation is greatly...

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Detalles Bibliográficos
Autores principales: Tanner, Bertrand C. W., Daniel, Thomas L., Regnier, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349719/
https://www.ncbi.nlm.nih.gov/pubmed/22589710
http://dx.doi.org/10.1371/journal.pcbi.1002506