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Functional Centromeres Determine the Activation Time of Pericentric Origins of DNA Replication in Saccharomyces cerevisiae

The centromeric regions of all Saccharomyces cerevisiae chromosomes are found in early replicating domains, a property conserved among centromeres in fungi and some higher eukaryotes. Surprisingly, little is known about the biological significance or the mechanism of early centromere replication; ho...

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Detalles Bibliográficos
Autores principales: Pohl, Thomas J., Brewer, Bonita J., Raghuraman, M. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349730/
https://www.ncbi.nlm.nih.gov/pubmed/22589733
http://dx.doi.org/10.1371/journal.pgen.1002677