Cargando…

Histone H1 Depletion Impairs Embryonic Stem Cell Differentiation

Pluripotent embryonic stem cells (ESCs) are known to possess a relatively open chromatin structure; yet, despite efforts to characterize the chromatin signatures of ESCs, the role of chromatin compaction in stem cell fate and function remains elusive. Linker histone H1 is important for higher-order...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yunzhe, Cooke, Marissa, Panjwani, Shiraj, Cao, Kaixiang, Krauth, Beth, Ho, Po-Yi, Medrzycki, Magdalena, Berhe, Dawit T., Pan, Chenyi, McDevitt, Todd C., Fan, Yuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349736/
https://www.ncbi.nlm.nih.gov/pubmed/22589736
http://dx.doi.org/10.1371/journal.pgen.1002691