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Acquisition Order of Ras and p53 Gene Alterations Defines Distinct Adrenocortical Tumor Phenotypes

Sporadic adrenocortical carcinomas (ACC) are rare endocrine neoplasms with a dismal prognosis. By contrast, benign tumors of the adrenal cortex are common in the general population. Whether benign tumors represent a separate entity or are in fact part of a process of tumor progression ultimately lea...

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Detalles Bibliográficos
Autores principales: Herbet, Maryline, Salomon, Aude, Feige, Jean-Jacques, Thomas, Michaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349738/
https://www.ncbi.nlm.nih.gov/pubmed/22589739
http://dx.doi.org/10.1371/journal.pgen.1002700