The Number of X Chromosomes Causes Sex Differences in Adiposity in Mice

Sexual dimorphism in body weight, fat distribution, and metabolic disease has been attributed largely to differential effects of male and female gonadal hormones. Here, we report that the number of X chromosomes within cells also contributes to these sex differences. We employed a unique mouse model...

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Detalles Bibliográficos
Autores principales: Chen, Xuqi, McClusky, Rebecca, Chen, Jenny, Beaven, Simon W., Tontonoz, Peter, Arnold, Arthur P., Reue, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349739/
https://www.ncbi.nlm.nih.gov/pubmed/22589744
http://dx.doi.org/10.1371/journal.pgen.1002709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349739/
https://www.ncbi.nlm.nih.gov/pubmed/22589744
http://dx.doi.org/10.1371/journal.pgen.1002709

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