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The Number of X Chromosomes Causes Sex Differences in Adiposity in Mice
Sexual dimorphism in body weight, fat distribution, and metabolic disease has been attributed largely to differential effects of male and female gonadal hormones. Here, we report that the number of X chromosomes within cells also contributes to these sex differences. We employed a unique mouse model...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349739/ https://www.ncbi.nlm.nih.gov/pubmed/22589744 http://dx.doi.org/10.1371/journal.pgen.1002709 |