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Neurospora COP9 Signalosome Integrity Plays Major Roles for Hyphal Growth, Conidial Development, and Circadian Function

The COP9 signalosome (CSN) is a highly conserved multifunctional complex that has two major biochemical roles: cleaving NEDD8 from cullin proteins and maintaining the stability of CRL components. We used mutation analysis to confirm that the JAMM domain of the CSN-5 subunit is responsible for NEDD8...

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Detalles Bibliográficos
Autores principales: Zhou, Zhipeng, Wang, Ying, Cai, Gaihong, He, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349749/
https://www.ncbi.nlm.nih.gov/pubmed/22589747
http://dx.doi.org/10.1371/journal.pgen.1002712