Nitazoxanide Stimulates Autophagy and Inhibits mTORC1 Signaling and Intracellular Proliferation of Mycobacterium tuberculosis

Tuberculosis, caused by Mycobacterium tuberculosis infection, is a major cause of morbidity and mortality in the world today. M. tuberculosis hijacks the phagosome-lysosome trafficking pathway to escape clearance from infected macrophages. There is increasing evidence that manipulation of autophagy,...

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Detalles Bibliográficos
Autores principales: Lam, Karen K. Y., Zheng, Xingji, Forestieri, Roberto, Balgi, Aruna D., Nodwell, Matt, Vollett, Sarah, Anderson, Hilary J., Andersen, Raymond J., Av-Gay, Yossef, Roberge, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349752/
https://www.ncbi.nlm.nih.gov/pubmed/22589723
http://dx.doi.org/10.1371/journal.ppat.1002691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349752/
https://www.ncbi.nlm.nih.gov/pubmed/22589723
http://dx.doi.org/10.1371/journal.ppat.1002691

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