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Adenovirus adenine nucleotide translocator-2 shRNA effectively induces apoptosis and enhances chemosensitivity by the down-regulation of ABCG2 in breast cancer stem-like cells

Cancer stem cells (CSCs) are resistant to chemo- and radio-therapy, and can survive to regenerate new tumors. This is an important reason why various anti-cancer therapies often fail to completely control tumors, although they kill and eliminate the bulk of cancer cells. In this study, we determined...

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Detalles Bibliográficos
Autores principales: Jang, Ji-Young, Kim, Min-Kyoung, Jeon, Yoon-Kyung, Joung, Yoon-Ki, Park, Ki-Dong, Kim, Chul-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349907/
https://www.ncbi.nlm.nih.gov/pubmed/22198296
http://dx.doi.org/10.3858/emm.2012.44.4.019