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Expression of Tight Junction and Drug Efflux Transporter Proteins in an in vitro Model of Human Blood–Brain Barrier

Interendothelial cell tight junctions (TJs) proteins contribute to maintain the structural and functional integrity of the blood–brain barrier (BBB) and several efflux transporters regulate transport of compounds across BBB. A unique double compartment-model of the BBB, consisting of cerebral endoth...

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Detalles Bibliográficos
Autores principales: Cioni, Chiara, Turlizzi, Elisa, Zanelli, Ugo, Oliveri, Giuseppe, Annunziata, Pasquale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350029/
https://www.ncbi.nlm.nih.gov/pubmed/22593745
http://dx.doi.org/10.3389/fpsyt.2012.00047