Mitochondrial cyclophilin-D as a potential therapeutic target for post-myocardial infarction heart failure

The pharmacological inhibition or genetic ablation of cyclophilin-D (CypD), a critical regulator of the mitochondrial permeability transition pore (mPTP), confers myocardial resistance to acute ischemia-reperfusion injury, but its role in post-myocardial infarction (MI) heart failure is unknown. The...

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Detalles Bibliográficos
Autores principales: Lim, Shiang Y, Hausenloy, Derek J, Arjun, Sapna, Price, Anthony N, Davidson, Sean M, Lythgoe, Mark F, Yellon, Derek M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350306/
https://www.ncbi.nlm.nih.gov/pubmed/21143389
http://dx.doi.org/10.1111/j.1582-4934.2010.01235.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350306/
https://www.ncbi.nlm.nih.gov/pubmed/21143389
http://dx.doi.org/10.1111/j.1582-4934.2010.01235.x

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