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Cis-Acting Polymorphisms Affect Complex Traits through Modifications of MicroRNA Regulation Pathways

Genome-wide association studies (GWAS) have become an effective tool to map genes and regions contributing to multifactorial human diseases and traits. A comparably small number of variants identified by GWAS are known to have a direct effect on protein structure whereas the majority of variants is...

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Detalles Bibliográficos
Autores principales: Arnold, Matthias, Ellwanger, Daniel C., Hartsperger, Mara L., Pfeufer, Arne, Stümpflen, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350471/
https://www.ncbi.nlm.nih.gov/pubmed/22606281
http://dx.doi.org/10.1371/journal.pone.0036694