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Cis-Acting Polymorphisms Affect Complex Traits through Modifications of MicroRNA Regulation Pathways
Genome-wide association studies (GWAS) have become an effective tool to map genes and regions contributing to multifactorial human diseases and traits. A comparably small number of variants identified by GWAS are known to have a direct effect on protein structure whereas the majority of variants is...
Autores principales: | Arnold, Matthias, Ellwanger, Daniel C., Hartsperger, Mara L., Pfeufer, Arne, Stümpflen, Volker |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350471/ https://www.ncbi.nlm.nih.gov/pubmed/22606281 http://dx.doi.org/10.1371/journal.pone.0036694 |
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