Depletion of Cytotoxic T-Cells Does Not Protect NUP98-HOXD13 Mice from Myelodysplastic Syndrome but Reveals a Modest Tumor Immunosurveillance Effect

Myelodysplastic syndrome (MDS) and aplastic anemia (AA) patients both present with symptoms of bone marrow failure. In many AA patients, these features are thought to result from an oligoclonal expansion of cytotoxic T-cells that destroy haematopoietic stem or progenitor cells. This notion is suppor...

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Detalles Bibliográficos
Autores principales: Gough, Sheryl M., Chung, Yang Jo, Aplan, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350481/
https://www.ncbi.nlm.nih.gov/pubmed/22606303
http://dx.doi.org/10.1371/journal.pone.0036876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350481/
https://www.ncbi.nlm.nih.gov/pubmed/22606303
http://dx.doi.org/10.1371/journal.pone.0036876

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