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Loss of Emerin Alters Myogenic Signaling and miRNA Expression in Mouse Myogenic Progenitors

Emerin is an integral membrane protein of the inner nuclear membrane. Mutations in emerin cause X-linked Emery-Dreifuss muscular dystrophy (EDMD), a disease characterized by skeletal muscle wasting and dilated cardiomyopathy. Current evidence suggests the muscle wasting phenotype of EDMD is caused b...

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Detalles Bibliográficos
Autores principales: Koch, Adam J., Holaska, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350500/
https://www.ncbi.nlm.nih.gov/pubmed/22606356
http://dx.doi.org/10.1371/journal.pone.0037262