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Structural Insights into Human Peroxisome Proliferator Activated Receptor Delta (PPAR-Delta) Selective Ligand Binding

Peroxisome proliferator activated receptors (PPARs δ, α and γ) are closely related transcription factors that exert distinct effects on fatty acid and glucose metabolism, cardiac disease, inflammatory response and other processes. Several groups developed PPAR subtype specific modulators to trigger...

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Detalles Bibliográficos
Autores principales: Batista, Fernanda A. H., Trivella, Daniela B. B., Bernardes, Amanda, Gratieri, Joyce, Oliveira, Paulo S. L., Figueira, Ana Carolina M., Webb, Paul, Polikarpov, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350516/
https://www.ncbi.nlm.nih.gov/pubmed/22606221
http://dx.doi.org/10.1371/journal.pone.0033643