Cargando…
Structural Insights into Human Peroxisome Proliferator Activated Receptor Delta (PPAR-Delta) Selective Ligand Binding
Peroxisome proliferator activated receptors (PPARs δ, α and γ) are closely related transcription factors that exert distinct effects on fatty acid and glucose metabolism, cardiac disease, inflammatory response and other processes. Several groups developed PPAR subtype specific modulators to trigger...
Autores principales: | Batista, Fernanda A. H., Trivella, Daniela B. B., Bernardes, Amanda, Gratieri, Joyce, Oliveira, Paulo S. L., Figueira, Ana Carolina M., Webb, Paul, Polikarpov, Igor |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350516/ https://www.ncbi.nlm.nih.gov/pubmed/22606221 http://dx.doi.org/10.1371/journal.pone.0033643 |
Ejemplares similares
-
Cellular and Biophysical Pipeline for the Screening of Peroxisome Proliferator-Activated Receptor Beta/Delta Agonists: Avoiding False Positives
por: Videira, Natália Bernardi, et al.
Publicado: (2018) -
Low-Resolution Molecular Models Reveal the Oligomeric State of the PPAR and the Conformational Organization of Its Domains in Solution
por: Bernardes, Amanda, et al.
Publicado: (2012) -
Molecular Characterization and Expression Analysis of the Peroxisome Proliferator Activated Receptor Delta (PPARδ) Gene before and after Exercise in Horse
por: Cho, Hyun-Woo, et al.
Publicado: (2015) -
Neuron-Specific Deletion of Peroxisome Proliferator-Activated Receptor Delta (PPARδ) in Mice Leads to Increased Susceptibility to Diet-Induced Obesity
por: Kocalis, Heidi E., et al.
Publicado: (2012) -
PPAR Beta/Delta and the Hallmarks of Cancer
por: Wagner, Nicole, et al.
Publicado: (2020)