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Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators

Reinforcement of actin stress fibers in response to mechanical stimulation depends on a posttranslational mechanism that requires the LIM protein zyxin. The C-terminal LIM region of zyxin directs the force-sensitive accumulation of zyxin on actin stress fibers. The N-terminal region of zyxin promote...

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Detalles Bibliográficos
Autores principales: Hoffman, Laura M., Jensen, Christopher C., Chaturvedi, Aashi, Yoshigi, Masaaki, Beckerle, Mary C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350550/
https://www.ncbi.nlm.nih.gov/pubmed/22456508
http://dx.doi.org/10.1091/mbc.E11-12-1057