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Characterizing the roles of Met31 and Met32 in coordinating Met4-activated transcription in the absence of Met30

Yeast sulfur metabolism is transcriptionally regulated by the activator Met4. Met4 lacks DNA-binding ability and relies on interactions with Met31 and Met32, paralogous proteins that bind the same cis-regulatory element, to activate its targets. Although Met31 and Met32 are redundant for growth in t...

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Detalles Bibliográficos
Autores principales: Carrillo, Emilio, Ben-Ari, Giora, Wildenhain, Jan, Tyers, Mike, Grammentz, Dilon, Lee, Traci A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350556/
https://www.ncbi.nlm.nih.gov/pubmed/22438580
http://dx.doi.org/10.1091/mbc.E11-06-0532