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Cell surface annexins regulate ADAM-mediated ectodomain shedding of proamphiregulin

A disintegrin and metalloproteinase (ADAM) is a family of enzymes involved in ectodomain shedding of various membrane proteins. However, the molecular mechanism underlying substrate recognition by ADAMs remains unknown. In this study, we successfully captured and analyzed cell surface transient asse...

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Detalles Bibliográficos
Autores principales: Nakayama, Hironao, Fukuda, Shinji, Inoue, Hirofumi, Nishida-Fukuda, Hisayo, Shirakata, Yuji, Hashimoto, Koji, Higashiyama, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350559/
https://www.ncbi.nlm.nih.gov/pubmed/22438584
http://dx.doi.org/10.1091/mbc.E11-08-0683