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Cell surface annexins regulate ADAM-mediated ectodomain shedding of proamphiregulin
A disintegrin and metalloproteinase (ADAM) is a family of enzymes involved in ectodomain shedding of various membrane proteins. However, the molecular mechanism underlying substrate recognition by ADAMs remains unknown. In this study, we successfully captured and analyzed cell surface transient asse...
Autores principales: | Nakayama, Hironao, Fukuda, Shinji, Inoue, Hirofumi, Nishida-Fukuda, Hisayo, Shirakata, Yuji, Hashimoto, Koji, Higashiyama, Shigeki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350559/ https://www.ncbi.nlm.nih.gov/pubmed/22438584 http://dx.doi.org/10.1091/mbc.E11-08-0683 |
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