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Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen

As with many other viruses, the initial cell attachment of rotaviruses, major causative agent of infantile gastroenteritis, is mediated by interactions with specific cellular glycans(1–4). The distally located VP8* domain of the rotavirus spike protein VP4(5) mediates such interactions. The existing...

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Detalles Bibliográficos
Autores principales: Hu, Liya, Crawford, Sue E., Czako, Rita, Cortes-Penfield, Nicolas W, Smith, David F., Le Pendu, Jacques, Estes, Mary K., Venkataram Prasad, B. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350622/
https://www.ncbi.nlm.nih.gov/pubmed/22504179
http://dx.doi.org/10.1038/nature10996