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Activation of the G-protein-coupled receptor GPR30 induces anxiogenic effects in mice, similar to oestradiol

RATIONALE: The influence of ovarian hormones on behaviour is well accepted, and oestrogen replacement therapy has proven to be beneficial in several cases of menopausal mood disorders. However, there are also some adverse effects of such a therapy, like anxiety and dysphoria. In fact, some women fee...

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Detalles Bibliográficos
Autores principales: Kastenberger, Iris, Lutsch, Christian, Schwarzer, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350630/
https://www.ncbi.nlm.nih.gov/pubmed/22143579
http://dx.doi.org/10.1007/s00213-011-2599-3