pncA mutations in clinical Mycobacterium tuberculosis isolates from Korea

BACKGROUND: Pyrazinamide (PZA) is among the first-line drugs for the treatment of tuberculosis. In vitro, it kills semidormant mycobacteria only at low pH. The purpose of this study was to compare PZA resistance with pyrazinamidase (PZase) activity and the genotype to better understand the molecular...

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Detalles Bibliográficos
Autores principales: Park, Soon Kew, Lee, Jung Yoo, Chang, Chulhun Ludgerus, Lee, Min Ki, Son, Han Chul, Kim, Cheol Min, Jang, Hyun Jung, Park, Hee Kyung, Jeong, Seok Hoon
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC33507/
https://www.ncbi.nlm.nih.gov/pubmed/11429043
http://dx.doi.org/10.1186/1471-2334-1-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC33507/
https://www.ncbi.nlm.nih.gov/pubmed/11429043
http://dx.doi.org/10.1186/1471-2334-1-4

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