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Mec1p associates with functionally compromised telomeres

In many organisms, telomere DNA consists of simple sequence repeat tracts that are required to protect the chromosome end. In the yeast Saccharomyces cerevisiae, tract maintenance requires two checkpoint kinases of the ATM family, Tel1p and Mec1p. Previous work has shown that Tel1p is recruited to f...

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Detalles Bibliográficos
Autores principales: Hector, Ronald E., Ray, Alo, Chen, Bo-Ruei, Shtofman, Rebecca, Berkner, Kathleen L., Runge, Kurt W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350766/
https://www.ncbi.nlm.nih.gov/pubmed/22289863
http://dx.doi.org/10.1007/s00412-011-0359-0