Plasticity and mTOR: Towards Restoration of Impaired Synaptic Plasticity in mTOR-Related Neurogenetic Disorders

Objective. To review the recent literature on the clinical features, genetic mutations, neurobiology associated with dysregulation of mTOR (mammalian target of rapamycin), and clinical trials for tuberous sclerosis complex (TSC), neurofibromatosis-1 (NF1) and fragile X syndrome (FXS), and phosphatas...

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Detalles Bibliográficos
Autores principales: Gipson, Tanjala T., Johnston, Michael V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350854/
https://www.ncbi.nlm.nih.gov/pubmed/22619737
http://dx.doi.org/10.1155/2012/486402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350854/
https://www.ncbi.nlm.nih.gov/pubmed/22619737
http://dx.doi.org/10.1155/2012/486402

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