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oxLDL Downregulates the Dendritic Cell Homing Factors CCR7 and CCL21

Introduction. Dendritic cells (DCs) and oxLDL play an important role in the atherosclerotic process with DCs accumulating in the plaques during plaque progression. Our aim was to investigate the role of oxLDL in the modulation of the DC homing-receptor CCR7 and endothelial-ligand CCL21. Methods and...

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Detalles Bibliográficos
Autores principales: Nickel, Thomas, Pfeiler, Susanne, Summo, Claudia, Kopp, Reinhard, Meimarakis, Georgios, Sicic, Zeljka, Lambert, Marius, Lackermair, Korbinian, David, Robert, Beiras-Fernandez, Andres, Kaczmarek, Ingo, Weis, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350855/
https://www.ncbi.nlm.nih.gov/pubmed/22619482
http://dx.doi.org/10.1155/2012/320953