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Histone H3 tail clipping regulates gene expression

Induction of gene expression in yeast and human cells involves changes in histone modifications associated with promoters. Here we identify a histone H3 endopeptidase activity in S. cerevisiae that may regulate these events. The endopeptidase cleaves H3 after alanine 21, generating a histone lacking...

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Detalles Bibliográficos
Autores principales: Santos-Rosa, Helena, Kirmizis, Antonis, Nelson, Christopher, Bartke, Till, Saksouk, Nehme, Cote, Jacques, Kouzarides, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350865/
https://www.ncbi.nlm.nih.gov/pubmed/19079264
http://dx.doi.org/10.1038/nsmb.1534