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Anti-Interleukin-1 Agents in Adult Onset Still's Disease

Interleukin 1β (IL-1β) is emerging as a master mediator of adult onset Still's disease (AOSD) pathogenesis. This pleiotropic cytokine, whose expression is under the control of the inflammasome pathway, has a wide type of effects. As a key mediator of innate immunity is a potent pyrogen and faci...

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Detalles Bibliográficos
Autores principales: Giampietro, Cecilia, Fautrel, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350963/
https://www.ncbi.nlm.nih.gov/pubmed/22611515
http://dx.doi.org/10.1155/2012/317820