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Quantification of particle-induced inflammatory stress response: a novel approach for toxicity testing of earth materials
BACKGROUND: Reactive oxygen species (ROS) are vital regulators of many cellular functions in the body. The intracellular ROS concentration is highly regulated by a balance between pro-oxidants and anti-oxidants. A chronic excess of pro-oxidants leads to elevated ROS concentrations and inflammation,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351022/ https://www.ncbi.nlm.nih.gov/pubmed/22513118 http://dx.doi.org/10.1186/1467-4866-13-4 |