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Quantification of particle-induced inflammatory stress response: a novel approach for toxicity testing of earth materials

BACKGROUND: Reactive oxygen species (ROS) are vital regulators of many cellular functions in the body. The intracellular ROS concentration is highly regulated by a balance between pro-oxidants and anti-oxidants. A chronic excess of pro-oxidants leads to elevated ROS concentrations and inflammation,...

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Detalles Bibliográficos
Autores principales: Harrington, Andrea D, Tsirka, Stella E, Schoonen, Martin AA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351022/
https://www.ncbi.nlm.nih.gov/pubmed/22513118
http://dx.doi.org/10.1186/1467-4866-13-4