Mechanisms behind Functional Avidity Maturation in T Cells

During an immune response antigen-primed B-cells increase their antigen responsiveness by affinity maturation mediated by somatic hypermutation of the genes encoding the antigen-specific B-cell receptor (BCR) and by selection of higher-affinity B cell clones. Unlike the BCR, the T-cell receptor (TCR...

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Detalles Bibliográficos
Autores principales: von Essen, Marina Rode, Kongsbak, Martin, Geisler, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351025/
https://www.ncbi.nlm.nih.gov/pubmed/22611418
http://dx.doi.org/10.1155/2012/163453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351025/
https://www.ncbi.nlm.nih.gov/pubmed/22611418
http://dx.doi.org/10.1155/2012/163453

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