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Antibody-mediated neutralization of Ebola virus can occur by two distinct mechanisms

Human Ebola virus causes severe hemorrhagic fever disease with high mortality and there is no vaccine or treatment. Antibodies in survivors occur early, are sustained, and can delay infection when transferred into nonhuman primates. Monoclonal antibodies (mAbs) from survivors exhibit potent neutrali...

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Detalles Bibliográficos
Autores principales: Shedlock, Devon J., Bailey, Michael A., Popernack, Paul M., Cunningham, James M., Burton, Dennis R., Sullivan, Nancy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351102/
https://www.ncbi.nlm.nih.gov/pubmed/20304456
http://dx.doi.org/10.1016/j.virol.2010.02.029