New methods for finding common insertion sites and co-occurring common insertion sites in transposon- and virus-based genetic screens

Insertional mutagenesis screens in mice are used to identify individual genes that drive tumor formation. In these screens, candidate cancer genes are identified if their genomic location is proximal to a common insertion site (CIS) defined by high rates of transposon or retroviral insertions in a g...

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Detalles Bibliográficos
Autores principales: Bergemann, Tracy L., Starr, Timothy K., Yu, Haoyu, Steinbach, Michael, Erdmann, Jesse, Chen, Yun, Cormier, Robert T., Largaespada, David A., Silverstein, Kevin A. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351147/
https://www.ncbi.nlm.nih.gov/pubmed/22241771
http://dx.doi.org/10.1093/nar/gkr1295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351147/
https://www.ncbi.nlm.nih.gov/pubmed/22241771
http://dx.doi.org/10.1093/nar/gkr1295

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