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C6 pyridinium ceramide influences alternative pre-mRNA splicing by inhibiting protein phosphatase-1

Alternative pre-mRNA processing is a central element of eukaryotic gene regulation. The cell frequently alters the use of alternative exons in response to physiological stimuli. Ceramides are lipid-signaling molecules composed of sphingosine and a fatty acid. Previously, water-insoluble ceramides we...

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Detalles Bibliográficos
Autores principales: Sumanasekera, Chiranthani, Kelemen, Olga, Beullens, Monique, Aubol, Brandon E., Adams, Joseph A., Sunkara, Manjula, Morris, Andrew, Bollen, Mathieu, Andreadis, Athena, Stamm, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351148/
https://www.ncbi.nlm.nih.gov/pubmed/22210893
http://dx.doi.org/10.1093/nar/gkr1289