A novel phage-encoded transcription antiterminator acts by suppressing bacterial RNA polymerase pausing

Gp39, a small protein encoded by Thermus thermophilus phage P23–45, specifically binds the host RNA polymerase (RNAP) and inhibits transcription initiation. Here, we demonstrate that gp39 also acts as an antiterminator during transcription through intrinsic terminators. The antitermination activity...

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Detalles Bibliográficos
Autores principales: Berdygulova, Zhanna, Esyunina, Daria, Miropolskaya, Nataliya, Mukhamedyarov, Damir, Kuznedelov, Konstantin, Nickels, Bryce E., Severinov, Konstantin, Kulbachinskiy, Andrey, Minakhin, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351154/
https://www.ncbi.nlm.nih.gov/pubmed/22238378
http://dx.doi.org/10.1093/nar/gkr1285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351154/
https://www.ncbi.nlm.nih.gov/pubmed/22238378
http://dx.doi.org/10.1093/nar/gkr1285

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