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A novel phage-encoded transcription antiterminator acts by suppressing bacterial RNA polymerase pausing
Gp39, a small protein encoded by Thermus thermophilus phage P23–45, specifically binds the host RNA polymerase (RNAP) and inhibits transcription initiation. Here, we demonstrate that gp39 also acts as an antiterminator during transcription through intrinsic terminators. The antitermination activity...
Autores principales: | Berdygulova, Zhanna, Esyunina, Daria, Miropolskaya, Nataliya, Mukhamedyarov, Damir, Kuznedelov, Konstantin, Nickels, Bryce E., Severinov, Konstantin, Kulbachinskiy, Andrey, Minakhin, Leonid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351154/ https://www.ncbi.nlm.nih.gov/pubmed/22238378 http://dx.doi.org/10.1093/nar/gkr1285 |
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