Young intragenic miRNAs are less coexpressed with host genes than old ones: implications of miRNA–host gene coevolution

MicroRNAs (miRNAs) have emerged as key regulators of gene expression. Intragenic miRNAs account for ∼50% of mammalian miRNAs. Classic studies reported that they are usually coexpressed with host genes. Here, using genome-wide miRNA and gene expression profiles from five sample sets, we show that evo...

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Detalles Bibliográficos
Autores principales: He, Chunjiang, Li, Zejuan, Chen, Ping, Huang, Hao, Hurst, Laurence D., Chen, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351155/
https://www.ncbi.nlm.nih.gov/pubmed/22238379
http://dx.doi.org/10.1093/nar/gkr1312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351155/
https://www.ncbi.nlm.nih.gov/pubmed/22238379
http://dx.doi.org/10.1093/nar/gkr1312

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