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Stoichiometry of MutS and MutL at unrepaired mismatches in vivo suggests a mechanism of repair

Mismatch repair (MMR) is an evolutionarily conserved DNA repair system, which corrects mismatched bases arising during DNA replication. MutS recognizes and binds base pair mismatches, while the MutL protein interacts with MutS–mismatch complex and triggers MutH endonuclease activity at a distal-stra...

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Detalles Bibliográficos
Autores principales: Elez, Marina, Radman, Miroslav, Matic, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351158/
https://www.ncbi.nlm.nih.gov/pubmed/22241777
http://dx.doi.org/10.1093/nar/gkr1298