Conformational and thermodynamic properties modulate the nucleotide excision repair of 2-aminofluorene and 2-acetylaminofluorene dG adducts in the NarI sequence

Nucleotide excision repair (NER) is a major repair pathway that recognizes and corrects various lesions in cellular DNA. We hypothesize that damage recognition is an initial step in NER that senses conformational anomalies in the DNA caused by lesions. We prepared three DNA duplexes containing the c...

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Detalles Bibliográficos
Autores principales: Jain, Vipin, Hilton, Benjamin, Patnaik, Satyakam, Zou, Yue, Chiarelli, M. Paul, Cho, Bongsup P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351159/
https://www.ncbi.nlm.nih.gov/pubmed/22241773
http://dx.doi.org/10.1093/nar/gkr1307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351159/
https://www.ncbi.nlm.nih.gov/pubmed/22241773
http://dx.doi.org/10.1093/nar/gkr1307

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